Two related studies have been carried out to determine the effect of (a) po
wder:liquid ratio and (b) relative amounts of cement on the extent of buffe
ring of a lactic acid storage solution using zinc polycarboxylate and glass
-ionomer cements (both water-activated). The effect of varying the powder:l
iquid ratio was found to be slight and not statistically significant. On th
e other hand, increasing the numbers of specimens in a given volume of stor
age solution was found to have a significant influence on the final pH (at
the 0.0005 level of significance). The fact that powder:liquid ratio did no
t affect the final pH led to the conclusion that attack occurs mainly at th
e matrix of these cements, confirming previous findings about the acid eros
ion process. The finding that increasing the relative amount of cement to a
cid storage solution strongly influenced pH suggested that, under clinical
conditions, buffering would be important. When five specimens were used, th
e final pH corresponded to that of arrested caries, from which it was concl
uded that these cements have the ability to be cariostatic in vivo.