Selection of alcohols through Plackett-Burman design in lipase-catalyzed synthesis of anthranilic acid esters

Authors
Babu, CVS Divakar, S
Citation
Cvs. Babu et S. Divakar, Selection of alcohols through Plackett-Burman design in lipase-catalyzed synthesis of anthranilic acid esters, J AM OIL CH, 78(1), 2001, pp. 49-52
Citations number
13
Categorie Soggetti
Agricultural Chemistry
Journal title
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
ISSN journal
0003021X → ACNP
Volume
78
Issue
1
Year of publication
2001
Pages
49 - 52
Database
ISI
SICI code
0003-021X(200101)78:1<49:SOATPD>2.0.ZU;2-0
Abstract
Lipase-catalyzed synthesis of esters of anthranilic acid was attempted by e mploying alcohols of carbon chain length C-1-C-18 using Plackett-Burman exp erimental design. Of the alcohols employed, methanol, decanol, cetyl alcoho l, and stearyl alcohols showed 99.9% significance. Esterification of anthra nilic acid with methanol gave the highest yield at 45.6%. This study allows the selection of better alcohols for esterification of anthranilic acid.