Culture of hepatocytes using non-woven PTFE fabric coated with copolymer of poly (amino acid)-urethane

Authors
Shiba, Y Mukaiyama, T Wang, CR Ohyama, T Zhang, Q Enosawa, S Matsumura, T Kodama, M
Citation
Y. Shiba et al., Culture of hepatocytes using non-woven PTFE fabric coated with copolymer of poly (amino acid)-urethane, KAG KOG RON, 27(1), 2001, pp. 134-136
Citations number
8
Categorie Soggetti
Chemical Engineering
Journal title
KAGAKU KOGAKU RONBUNSHU
ISSN journal
0386216X → ACNP
Volume
27
Issue
1
Year of publication
2001
Pages
134 - 136
Database
ISI
SICI code
0386-216X(200101)27:1<134:COHUNP>2.0.ZU;2-H
Abstract
In this study, rat primary hepatocytes were cultured on a non-woven PTFE fa bric coated with a copolymer of poly (amino acid)-urethane. (PAU) to examin e the expression of their original functions. In the culture dish, ammonium metabolic activity of hepatocytes cultured using the fabric coated with PA U is higher than that using collagen-coated polystyrene. It is also indicat ed that it is possible for hepatocytes to maintain the functions for long-t erm culture in the circulatory culture equipment with the fabric coated wit h PAU.