Background. There is a rare association between splenic hamartomas and hema
tological abnormalities with, to our knowledge, only 24 reported cases in t
he English literature.
Patients and methods. We report a case of a splenic hamartoma in a 14-year-
old boy associated with membranoproliferative glomerulonephritis, multiple
lobular capillary hemangiomas of the skin, hypertension, and anemia. Follow
ing imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was s
uspected, but malignancy could not be excluded. The lesion was removed by p
artial splenectomy, and pathological examination confirmed the presence of
a red pulp splenic hamartoma.
Results. The renal, hematological, and dermatological abnormalities resolve
d following removal of the splenic hamartoma. This is the first reported ca
se of a splenic hamartoma associated with renal, cutaneous, and hematologic
al abnormalities and only the second reported case of a symptomatic splenic
hamartoma treated by partial splenectomy.