Symptomatic splenic hamartoma with renal, cutaneous, and hematological abnormalities

Background. There is a rare association between splenic hamartomas and hema tological abnormalities with, to our knowledge, only 24 reported cases in t he English literature. Patients and methods. We report a case of a splenic hamartoma in a 14-year- old boy associated with membranoproliferative glomerulonephritis, multiple lobular capillary hemangiomas of the skin, hypertension, and anemia. Follow ing imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was s uspected, but malignancy could not be excluded. The lesion was removed by p artial splenectomy, and pathological examination confirmed the presence of a red pulp splenic hamartoma. Results. The renal, hematological, and dermatological abnormalities resolve d following removal of the splenic hamartoma. This is the first reported ca se of a splenic hamartoma associated with renal, cutaneous, and hematologic al abnormalities and only the second reported case of a symptomatic splenic hamartoma treated by partial splenectomy.