Background: Glaucoma in infants has many causes, Evaluation of the ana
tomy of the anterior segment of eyes with infantile glaucoma may help
to determine the pathogenesis of an infant's disease and influence the
rapeutic decisions. Methods: Eleven eyes of six infants with glaucoma
were evaluated with ultrasound biomicroscopy (UBM) to evaluate the ana
tomic characteristics and relationships of the anterior segment struct
ures. Results: The anterior chamber angle, iris, lens, ciliary body, a
nd posterior chamber angle could be imaged in detail. Elongated and an
teriorly placed ciliary processes were noted in all eight eyes with tr
abeculodysgenesis, There were no apparent anomalies in the trabecular
meshwork, or anterior chamber, In three eyes with dense corneal opacit
ies, ultrasound biomicroscopy showed severe anterior segment disorgani
zation and thin central corneas with posterior corneal excavation. Con
clusions: Ultrasound biomicroscopy is a useful non-invasive method for
evaluating infants with glaucoma in cases with corneal opacities. Thi
s information can help in surgical planning for glaucoma management.