G. Bandieramonte et al., LASER MICROSURGERY FOR SUPERFICIAL T1-T2 BASAL-CELL CARCINOMA OF THE EYELID MARGINS, Ophthalmology, 104(7), 1997, pp. 1179-1184
Background: Basal cell carcinoma (BCC), the most common malignancy of
the eyelid margins, poses therapeutic problems. Surgery, radiation the
rapy, and cryotherapy are the currently accepted methods for the treat
ment of this affliction. To verify the technical and clinical effectiv
eness of the surgical laser method, a specific approach was developed
by performing laser-combined procedures under microscopic control. Met
hods: A series of 26 patients underwent carbon dioxide (CO2) laser mic
rosurgical excision of 27 primary superficial BCCs of the eyelid margi
ns. Eighteen tumors were T-1 and 9 were T-2. The lesions were located
at the lid margins in 18 and at the canthus in 9 cases. The eyelash li
ne was involved in all cases, whereas intermarginal space was involved
in 17 cases, without extension to the conjunctival border. Six lesion
s were in the lacrimal region, Median linear extent of the lesion was
5 mm (range, 4-10 mm). Treatment was performed with the patient under
local anesthesia in a Day Hospital regimen. The authors used the micro
scope-mounted CO2 laser as a scalpel to excise the tumor mass, thus ob
taining the specimen for histologic evaluation. The authors treated th
e deep and lateral resection margins with laser vaporization and left
the wound bed to heal by secondary intention. Results: No significant
complications were observed. As full-thickness eyelid resections were
avoided, the authors noted conservation of lid function and cosmetic a
spect in all patients. With a median follow-up of 73 months (range, 18
-118), only one patient had tumor recurrence after 22 months. This tum
or, located at the outer canthus, had a second microsurgical laser exc
ision, and the patient is disease tree 51 months after the last treatm
ent. Conclusions: Laser microsurgery appears to be a safe and effectiv
e treatment method for primary superficial T1 and T2 BCC of the eyelid
margins without conjunctival extension.