R. Thuret et al., Progression of stage 1 non-seminomatous germ cell tumours during surveillance. A case report. Place of positron emission tomography., PROG UROL, 10(6), 2000, pp. 1224-1227
Surveillance is one of the options proposed in the management of stage 1 no
n-seminomatous germ cell tumours when there is only a low risk of progressi
on. No consensus has yet been reached concerning the modalities of this sur
veillance and several protocols are available, including the CCAFU protocol
.
The presence of recurrences in this population at low risk of progression,
estimated to be 5%, accounts for the continuing research for more precise p
redictive factors of occult metastases. Although several studies appear to
indicate a useful predictive value for some of these factors, their applica
tion in clinical practice still appears to be difficult.
PET metabolic imaging (positron emission tomography) could constitute a new
approach to staging of these tumours, allowing the detection of tumour sit
es by an increase of carbohydrate metabolism of malignant cells. However, n
o study is yet available to define the real place of this technique.