The scientific basis of tension- type headache suffers from the lack of pre
cise pathophysiological knowledge and the heterogenecity of this disorder.
Treatment of acute tension-type headache episodes is more effective with an
NSAIDs (ibuprofen 400-800mg, naproxen 550-825mg, ketoprofen 50-75mg) than
with aspirin or paracetamol. Caffein containing preparations of NSAIDs are
slightly superior, but should not be taken frequently to avoid headache chr
onification. For chronic tension-type headache, relaxation therapies with E
MG biofeedback and tricyclics have about the same efficacy rate of 40-50p.1
00. Physical therapy and acupuncture are in general less effective. There i
s thus clearly a need for better strategies, e.g. combination of available
therapies and novel approaches.