Huntington disease in Burkina Faso.

Authors
Kabore, J Ouedraogo, A
Citation
J. Kabore et A. Ouedraogo, Huntington disease in Burkina Faso., REV NEUROL, 156(12), 2000, pp. 1157-1158
Citations number
12
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
REVUE NEUROLOGIQUE
ISSN journal
00353787 → ACNP
Volume
156
Issue
12
Year of publication
2000
Pages
1157 - 1158
Database
ISI
SICI code
0035-3787(200012)156:12<1157:HDIBF>2.0.ZU;2-B
Abstract
Four cases of Huntington's disease in two families seen in Burkino Faso, a country in western Africa, are described. All four patients were black Afri cans aged 43, 42, 38 and 33 years. The clinical presentation was typical wi th chorea and episodes of psychiatric disorders. Molecular genetics of one family showed abnormal expansion of CAG repeats on IT15 in three patients. Separate mutations are likely to be the origin of Huntington's disease in B urkino Faso.