Haptoglobin phenotype as a predictor of restenosis after percutaneous transluminal coronary angioplasty

We have demonstrated that a genetic polymorphism in the antioxidant protein haptoglobin is important in determining which patients develop restenosis after percutaneous transluminal coronary angioplasty. Knowledge of the hapt oglobin phenotype may be useful in the assessment and utilization of new th erapies to reduce restenosis, particularly in patients who are homozygous f or the haptoglobin 2 allele.