Rhabdomyolysis following cardiopulmonary bypass and treatment with enoximone in a patient susceptible to malignant hyperthermia

Authors
Riess, FC Fiege, M Moshar, S Bergmann, H Bleese, N Kormann, J Weisshorn, R Wappler, F
Citation
Fc. Riess et al., Rhabdomyolysis following cardiopulmonary bypass and treatment with enoximone in a patient susceptible to malignant hyperthermia, ANESTHESIOL, 94(2), 2001, pp. 355-357
Citations number
14
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ANESTHESIOLOGY
ISSN journal
00033022 → ACNP
Volume
94
Issue
2
Year of publication
2001
Pages
355 - 357
Database
ISI
SICI code
0003-3022(200102)94:2<355:RFCBAT>2.0.ZU;2-H
Abstract
SEVERE hypercapnia, muscle rigidity, hyperthermia, and rhabdomyolysis chara cterize malignant hyperthermia (MH) in fulminant form.(1) However, during c ardiac operations using cardiopulmonary bypass (CPB), typical symp toms of MH may not be present. We observed a patient undergoing aortic valve replac ement, in whom severe postoperative rhabdomyolysis and arrhythmias develope d after treatment with enoximone during CPB and cardioplegic arrest. Subseq uently, In vitro contracture testing showed that the patient was susceptibl e to MH.