Autoantibodies associated with atherosclerosis

Atherosclerosis is a multifactorial pathological process. In recent years, the immune factors associated with its initiation and progression have been investigated intensively. Several autoantigens and their respective autoan tibodies have been suggested as factors in atherogenesis. This manuscript p rovides a review of autoantibodies directed towards oxidized low-density li poprotein (oxLDL), cardiolipin, beta2-glycoprotein-I and hear-shock protein 60/45, and their association with human and murine atherosclerosis.