Biological activity of Feijoa peel extracts

Authors
Motohashi, N Kawase, M Shirataki, Y Tani, S Saito, S Sakagami, H Kurihara, T Nakashima, H Wolfard, K Mucsi, I Varga, A Molnar, J
Citation
N. Motohashi et al., Biological activity of Feijoa peel extracts, ANTICANC R, 20(6B), 2000, pp. 4323-4329
Citations number
28
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
ANTICANCER RESEARCH
ISSN journal
02507005 → ACNP
Volume
20
Issue
6B
Year of publication
2000
Pages
4323 - 4329
Database
ISI
SICI code
0250-7005(200011/12)20:6B<4323:BAOFPE>2.0.ZU;2-N
Abstract
Fractionated extracts of Feijoa peels were studied for cytotoxic activity, anti-human immunodeficiency vines (HIV) activity and antibacterial activity . Two most cytotoxic fractions A3 of acetone extract and M2 of methanol ext ract had potent inhibitory activity against Gram-positive and Gram-negative bacteria as well as fungi rested. Fraction A4 of acetone extract showed mu ltidrug resistance (MDR)-reversal activity comparable with that of verapami l (positive control). These results indicate the therapeutic value of Feijo a peel extracts as potential antimicrobial and MDR-modulating agents.