T-LYMPHOCYTE POPULATIONS IN THE BLOOD OF CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS-INFECTED GOATS

Authors
GREZEL D FORESTIER J GUIGUEN F MORNEX JF
Citation
D. Grezel et al., T-LYMPHOCYTE POPULATIONS IN THE BLOOD OF CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS-INFECTED GOATS, Veterinary immunology and immunopathology, 57(1-2), 1997, pp. 99-104
Citations number
19
Categorie Soggetti
Immunology,"Veterinary Sciences
Journal title
Veterinary immunology and immunopathology → ACNP
ISSN journal
01652427
Volume
57
Issue
1-2
Year of publication
1997
Pages
99 - 104
Database
ISI
SICI code
0165-2427(1997)57:1-2<99:TPITBO>2.0.ZU;2-1
Abstract
The effect of natural infection by Caprine Arthritis Encephalitis Viru s on the phenotypic pattern of T lymphocytes in peripheral blood was s tudied in a herd of 127 milking goats by flow cytometry. Total leukocy te and T-lymphocyte numbers tend to decrease with age, with only small changes in the CD4/CD8 ratio. The lymphocyte phenotypes show no stron g correlation with seropositivity to CAEV or the presence of clinical symptoms, suggesting that this macrophage-tropic lentivirus does not g reatly affect the lymphocyte population. (C) 1997 Elsevier Science B.V .