MALIC-ACID - A CONVENIENT PRECURSOR FOR THE SYNTHESIS OF PEPTIDE SECONDARY STRUCTURE MIMETICS

Authors
KIM HO LUM C LEE MS
Citation
Ho. Kim et al., MALIC-ACID - A CONVENIENT PRECURSOR FOR THE SYNTHESIS OF PEPTIDE SECONDARY STRUCTURE MIMETICS, Tetrahedron letters, 38(28), 1997, pp. 4935-4938
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
28
Year of publication
1997
Pages
4935 - 4938
Database
ISI
SICI code
0040-4039(1997)38:28<4935:M-ACPF>2.0.ZU;2-H
Abstract
Syntheses of optically active ether-linked beta-lactams and aza-prolin e analogues via 4-bromo-2-hydroxybutanoic acid esters derived from (S) - or (R)-malic acid are described. From these intermediates peptide se condary structure mimetics can be synthesized. (C) 1997 Elsevier Scien ce Ltd.