New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position

Authors
Cho, A Glinka, TW Ludwikow, M Fan, AT Wang, M Hecker, SJ
Citation
A. Cho et al., New anti-MRSA cephalosporins with a basic aminopyridine at the C-7 position, BIOORG MED, 11(2), 2001, pp. 137-140
Citations number
19
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
2
Year of publication
2001
Pages
137 - 140
Database
ISI
SICI code
0960-894X(20010122)11:2<137:NACWAB>2.0.ZU;2-7
Abstract
Incorporation of a basic aminopyridine into the C-7 position of 3-(amine-su bstituted arylthio)-3-norcephalosporins, as in 3, afforded high potency aga inst MRSA and acceptable solubility for intravenous administration. (C) 200 1 Elsevier Science Ltd. All rights reserved.