Chemical synthesis of UDP-beta-L-arabinofuranose and its turnover to UDP-beta-L-arabinopyranose by UDP-galactopyranose mutase

Authors
Zhang, QB Liu, HW
Citation
Qb. Zhang et Hw. Liu, Chemical synthesis of UDP-beta-L-arabinofuranose and its turnover to UDP-beta-L-arabinopyranose by UDP-galactopyranose mutase, BIOORG MED, 11(2), 2001, pp. 145-149
Citations number
24
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
2
Year of publication
2001
Pages
145 - 149
Database
ISI
SICI code
0960-894X(20010122)11:2<145:CSOUAI>2.0.ZU;2-A
Abstract
Uridine-5'-diphospho-beta -L-arabinofuranose, a possible donor of L-arabino furanose residues in plants, was synthesized. This compound, in the presenc e of UDP-galactopyranose mutase, underwent interconversion with UDP-beta -L -arabinopyranose that is a likely precursor of L-arabinofuranose in vivo. T his result provided a working model for the biogenesis of arabinofuranose i n plants. (C) 2001 Elsevier Science Ltd. All rights reserved.