2,2-dimethyl-4,5-diaryl-3(2H) furanone derivatives as selective cyclo-oxygenase-2 inhibitors

Authors
Shin, SS Noh, MS Byun, YJ Choi, JK Kim, JY Lim, KM Ha, JY Kim, JK Lee, CH Chung, S
Citation
Ss. Shin et al., 2,2-dimethyl-4,5-diaryl-3(2H) furanone derivatives as selective cyclo-oxygenase-2 inhibitors, BIOORG MED, 11(2), 2001, pp. 165-168
Citations number
15
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
2
Year of publication
2001
Pages
165 - 168
Database
ISI
SICI code
0960-894X(20010122)11:2<165:2FDASC>2.0.ZU;2-D
Abstract
A series of 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-phenyl-3(2H)furanon es was prepared and evaluated for their ability to inhibit cyclo-oxygenase- 2 (COX-2) (C) 2001 Elsevier Science Ltd. All rights reserved.