Umbilical cord blood for allogeneic transplantation in children and adults

Early clinical reports outlining outcomes for primarily pediatric patients undergoing UCB transplantation, point to delayed time to hematopoietic reco very, and favorable incidence and severity of graft-versus-host disease. In tensive clinical and laboratory research is ongoing focused on strategies t o foster UCB allogeneic donor engraftment, thereby allowing wider applicati on of this stem cell source for patients requiring allogeneic transplantati on.