A novel NMR method for screening soluble compound libraries

Authors
Hodge, P Monvisade, P Morris, GA Preece, I
Citation
P. Hodge et al., A novel NMR method for screening soluble compound libraries, CHEM COMMUN, (03), 2001, pp. 239-240
Citations number
19
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
03
Year of publication
2001
Pages
239 - 240
Database
ISI
SICI code
1359-7345(2001):03<239:ANNMFS>2.0.ZU;2-#
Abstract
The use of high resolution diffusion-ordered NMR spectroscopy (HR-DOSY) to detect association between a soluble polymer and different components of sm all libraries of soluble compounds is illustrated for libraries bindingresp ectively to weakly acidic and weakly basic polymers.