Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen

Authors
Baek, MG Rittenhouse-Olson, K Roy, R
Citation
Mg. Baek et al., Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen, CHEM COMMUN, (03), 2001, pp. 257-258
Citations number
19
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
03
Year of publication
2001
Pages
257 - 258
Database
ISI
SICI code
1359-7345(2001):03<257:SAABPO>2.0.ZU;2-R
Abstract
Breast cancer marker T-antigen (Gal(beta1-3)alpha GalNAc) was prepared as a n allyl glycoside that was transformed into an active ester and coupled to a series of poly(amidoamine) dendrimers showing strong binding to mouse mon oclonal IgG antibodies and serving as useful coating antigens in microtiter plates.