Pd(en) as a sequence-selective molecular pinch for alpha-helical peptides

Authors
Hamachi, I Kasagi, N Kiyonaka, S Nagase, T Mito-oka, Y Shinkai, S
Citation
I. Hamachi et al., Pd(en) as a sequence-selective molecular pinch for alpha-helical peptides, CHEM LETT, (1), 2001, pp. 16-17
Citations number
16
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
1
Year of publication
2001
Pages
16 - 17
Database
ISI
SICI code
0366-7022(20010105):1<16:PAASMP>2.0.ZU;2-9
Abstract
A palladium(II)(ethylenediamine) complex was found to selectively stabilize alpha -helix conformation of peptides having two histidine (His) residues at i and i + (3 or 4) positions, whereas the helix conformation of the othe r peptides having one or two His at different positions is destabilized.