Rhodococcus equi infections in immunocompetent hosts: Case report and review

Citation
I. Kedlaya et al., Rhodococcus equi infections in immunocompetent hosts: Case report and review, CLIN INF D, 32(3), 2001, pp. E39-E46
Citations number
30
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
32
Issue
3
Year of publication
2001
Pages
E39 - E46
Database
ISI
SICI code
1058-4838(20010201)32:3<E39:REIIIH>2.0.ZU;2-O
Abstract
Rhodococcus equi is an unusual cause of infection in humans. Infection in i mmunocompetent patients is extremely rare-only 19 cases in immunocompetent hosts have been reported. Localized infections represent nearly 50% of repo rted cases. Pulmonary infections account for only 42% of infections in immu nocompetent hosts, compared with 84% of infections in immunocompromised hos ts. The mortality rate among immunocompetent patients is similar to 11%, co mpared with rates of 50%-55% among human immunodeficiency virus (HIV)-infec ted patients and 20%-25% among non-HIV-infected immunocompromised patients. Treatment of infections in immunocompetent hosts depends on the site of in fection. Serious infections need to be treated with combinations of parente ral antibiotics, followed by combinations of oral antibiotics. Surgical tre atment is necessary for certain types of local infections. We report a pulm onary infection due to R. equi in an immunocompetent patient, and we review all reported cases of R. equi infection in immunocompetent hosts.