Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome

We present a case report of a patient who had acquired immunodeficiency syn drome (AIDS) and Campylobacter fetus infection with a number of unusual cli nical and microbiological features. The patient had prominent gastrointesti nal symptoms, splenic infarction, splenomegaly with hypersplenism, and hemo phagocytic histiocytosis in the spleen and lymph nodes; the organism displa yed growth on Campy- selective blood agar, thermotolerance, and resistance to quinolones, piperacillin/tazobactam, ceftazidime, and erythromycin.