How should we use the short acting insulin analog in external pumps?

External pump treatment improves glycemic control, particularly thanks to t he continuous basal rate. The pharmacokinetics of the short-acting insulin analog lispro allow a better control of post-prandial hyperglycemia than re gular insulin. The use of the short-acting insulin analog in the pump impro ves HbA1c and blood glucose stability, without increasing the risk of hypog lycemia. Frequent blood glucose self-monitoring is required in order to opt imize insulin adjustments, using the retro-active method. Systematic monito ring of urine ketones is also required, for an early detection of any inter ruption in insulin delivery. Under these conditions, this modality of inten sified treatment seems very efficient.