LEUKEMIA INHIBITORY FACTOR (LIF) MESSENGER-RNA-EXPRESSING NEURONAL SUBPOPULATIONS IN ADULT-RAT BASAL FOREBRAIN

Authors
LEMKE R GADIENT RA PATTERSON PH BIGL V SCHLIEBS R
Citation
R. Lemke et al., LEUKEMIA INHIBITORY FACTOR (LIF) MESSENGER-RNA-EXPRESSING NEURONAL SUBPOPULATIONS IN ADULT-RAT BASAL FOREBRAIN, Neuroscience letters, 229(1), 1997, pp. 69-71
Citations number
19
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
229
Issue
1
Year of publication
1997
Pages
69 - 71
Database
ISI
SICI code
0304-3940(1997)229:1<69:LIF(MN>2.0.ZU;2-5
Abstract
We have previously found leukemia inhibitory factor (LIF) mRNA in neur ons of the adult rat brain. To identify which neuronal subpopulations are expressing LIF transcripts, non-radioactive in situ hybridization was combined with immunocytochemistry for various neuronal markers. St udying the rat basal forebrain and cerebral cortex, we find LIF mRNA i s expressed in both cholinergic and GABAergic neurons. These data sugg est a role for LIF in the function of these mature neurons. (C) 1997 E lsevier Science Ireland Ltd.