Sm. Thomas et al., BRITISH BIOTECH - HOW MUCH VALUE IS THERE IN METALLOPROTEINASE INHIBITORS, Expert opinion on therapeutic patents, 7(7), 1997, pp. 687-693
The value of British Biotech is built upon two matric: metalloproteina
se (MMP) inhibitors, Marimastat and Batimastat, both in clinical trial
s. These are supported by a strong patent portfolio in the area. A sec
ond aspect of the company's activity is in the area of platelet activa
ting factor (PAF) antagonists. Two genetically engineered proteins, a
modified plasminogen thrombolytic and an inhibitor of stem cell prolif
eration make up the pipeline.