Lipid peroxidation in nicotinamide-deficient and nicotinamide-supplementedrats

Authors
Melo, SS Meirelles, MS Jordao, AF Vannucchi, H
Citation
Ss. Melo et al., Lipid peroxidation in nicotinamide-deficient and nicotinamide-supplementedrats, INT J VIT N, 70(6), 2000, pp. 321-323
Citations number
10
Categorie Soggetti
Food Science/Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
ISSN journal
03009831 → ACNP
Volume
70
Issue
6
Year of publication
2000
Pages
321 - 323
Database
ISI
SICI code
0300-9831(200012)70:6<321:LPINAN>2.0.ZU;2-#
Abstract
Supplementation or deficiency of nicotinamide in rats may interfere with th e oxidative balance, with excess leading to greater lipid peroxidation, mea sured by TEARS, and deficiency causing a greater consumption of antioxidant s such as vitamin E and glutathione. Urinary N-methylnicotinamide excretion was much more marked in the supplemented group, whereas the difference bet ween deficient and control animals was nonsignificant.