Study on preparation of monodispersed poly(styrene-co-N-dimethylaminoethylmethacrylate) composite microspheres by SPG (Shirasu porous glass) emulsification technique

Monodispersed poly(styrene-co-N-dimethylaminoethyl methacrylate) [P(St-DMAE MA)] composite microspheres were prepared by employing a Shirasu Porous Gla ss (SPG) emulsification technique. A mixture of monomer, hexadecane (HD), a nd initiator N,N'-azobis(2, 4-dimethylvaleronitrile) (ADVN) was used as a d ispersed phase and an aqueous phase containing stabilizer [poly(vinyl pyrro lidone) (PVP) or poly(vinyl alcohol)(PVA)], sodium lauryl sulfate (SLS), an d water-soluble inhibitor [hydroquinone (HQ), diaminophenylene (DAP), or so dium nitrite (NaNO2)], was used as a continuous phase. The dispersed phase was permeated through the uniform pores of SPG membrane into the continuous phase by a gas pressure to form the uniform droplets. Then, the droplets w ere polymerized at 70 degreesC. The effects of inhibitor, stabilizer, ADVN, and DMAEMA on the secondary nucleation, DMAEMA fraction in the polymer, co nversion, and morphologies of the particles were investigated. It was found that the secondary nucleation was prevented effectively in the presence of HQ or DAP when PVP was used as the stabilizer. The secondary particle was observed when ADVN amount was raised to 0.3 g (/18 g monomer); however, no secondary nucleation occurred even by increasing DMAEMA fraction to 10 wt % . This result implied that the diffusion of ADVN into the aqueous phase was a main factor responsible to the secondary nucleation more than that of DM AEMA. The hollow particles were obtained when NaNO2 was used, while one-hol e particles formed in the other cases. By adding crosslinking agent, the ho le disappeared and the monomer conversion was improved. (C) 2001 John Wiley & Sons, Inc.