We review our experience with minimally invasive direct access (MIDA) heart
valve surgery in 518 patients. Two hundred fifty-two patients underwent MI
DA aortic valve replacement (AVR) or repair and 266 underwent MIDA mitral v
alve repair or replacement. Among the 250 AVRs, 157 (63%) were men, aged 63
.2 +/- 14.6 years, NYHA functional Class 2.4 +/- 0.8. The surgical approach
was right parasternal in 36 (14%) or upper hemisternotomy in 216 (86%). Th
ere were four (2%) operative deaths. Perioperative complications included 1
4 (5.6%) reexplorations for bleeding, 7 (3%) chest wound infections, 5 (2%)
strokes, and 1 (0.4%) external iliac vein injury. Follow-up was complete i
n 193 (77%) patients, with a mean follow-up of 12 +/- 8 months. Late compli
cations included 2 (0.8%) nonfatal myocardial infarctions, 4 (2%) reoperati
ons for, respectively, 2 pericardial complications, 1 paravalvar leak, and
1 infected valve. There were five (2%) late deaths from congestive heart fa
ilure, pneumonia, hemorrhage, aneurysm, and cancer. Mean follow-up NYHA Cla
ss was 1.4 +/- 0.6. For the 266 mitral patients, 145 (54.5%) were men, age
58.7 +/- 13.6 years, functional Class 2.3 +/- 0.5. The surgical approach wa
s right parasternal in 195 (73%), lower hemisternotomy in 53 (20%), right s
ubmammary thoracotomy in 9 (3.4%), or full sternotomy through a small skin
incision in 9 (3.4%). There were 2 (0.8%) operative deaths. Perioperative c
omplications included 4 (1.5%) reoperations for bleeding, 4 (1.5%) strokes,
and 5 (2%) wound infections, and 3 (1%) ascending aortic complications. Fo
llowup was complete in 202 (76%) patients with a mean follow-up of 9.5 +/-
6.4 months. Late complications included one (0.4%) nonfatal myocardial infa
rction and three (1%) reoperations all converting repairs to replacements.
There were three (1%) late deaths from suicide, pneumonia, and sudden death
, respectively. Mean follow-up NYHA functional Class was 1.3 +/- 0.5. We co
nclude that MIDA heart valve surgery is safe and effective for the majority
of patients requiring isolated elective aortic or mitral valve surgery.