S. Kiyoyama et al., Preparation of cross-linked microcapsules entrapping inorganic salt by in-situ polymerization in (W/O/W) emulsion system, J CHEM EN J, 34(1), 2001, pp. 36-42
Cross-linked microcapsules entrapping ascorbic acid magnesium salt as a cor
e material are prepared by in-situ copolymerization of styrene and divinylb
enzene in a (W/O/W) emulsion system, The effects of the preparation conditi
ons of the microcapsules on the capsule morphologies, the entrapment effici
ency and release profiles of the core material are investigated, The entrap
ment efficiency of the core material is improved by lowering the volume fra
ction of the dispersion phase in the (W/O) emulsion and adding the salt to
the outer aqueous phase when tricalcium phosphate is used as the dispersion
stabilizer. Both the entrapment efficiency of the core material and the in
ternal morphologies of the microcapsules affect the release profiles of the
core material.