Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity

Authors
Mimaki, Y Watanabe, K Ando, Y Sakuma, C Sashida, Y Furuya, S Sakagami, H
Citation
Y. Mimaki et al., Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity, J NAT PROD, 64(1), 2001, pp. 17-22
Citations number
13
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
1
Year of publication
2001
Pages
17 - 22
Database
ISI
SICI code
0163-3864(200101)64:1<17:FGASSF>2.0.ZU;2-N
Abstract
Phytochemical analysis of the leaves of Cestrum nocturnum (Solanaceae) resu lted in the isolation of two new flavonol glycosides (1, 2) and seven stero idal saponins (3-9), including four new ones (4, 6, 7, and 9). The structur es of the new compounds were determined by spectroscopic analysis, includin g 2D NMR data, and the results of hydrolytic cleavage. Cytotoxic activities of the isolated compounds against human oral squamous cell carcinoma-(HSC- 2) cells and normal human gingival fibroblasts are reported.