New co-metabolites of the streptazolin pathway

Authors
Puder, C Loya, S Hizi, A Zeeck, A
Citation
C. Puder et al., New co-metabolites of the streptazolin pathway, J NAT PROD, 64(1), 2001, pp. 42-45
Citations number
22
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
1
Year of publication
2001
Pages
42 - 45
Database
ISI
SICI code
0163-3864(200101)64:1<42:NCOTSP>2.0.ZU;2-D
Abstract
Variation of the culture conditions of Streptomyces sp. strain Al, which pr oduces streptazolin (1), resulted in the isolation of four new co-metabolit es: 5-O-(beta -D-xylopyranosyl)streptazolin (3), 9-hydroxystreptazolin (4), 13-hydroxystreptazolin (5), and streptenol E (6). Their structures were es tablished by spectroscopic and chemical methods. The possible biosynthetic relationship between the streptazolins and the streptenols is discussed.