Two new flavonoid alkaloids, aquiledine (1) and isoaquiledine (2), were iso
lated from the whole herb of Aquilegia ecalcarata, and their structures wer
e determined by detailed spectral analysis. Three known flavonoids were als
o isolated from this extract-apigenin, apigenin-7,4'-dimethyl ether, and lu
teolin-and have not been reported previously from A. ecalcarata.