Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae

Authors
Kuroda, M Mimaki, Y Yokosuka, A Sashida, Y Beutler, JA
Citation
M. Kuroda et al., Cytotoxic cholestane glycosides from the bulbs of Ornithogalum saundersiae, J NAT PROD, 64(1), 2001, pp. 88-91
Citations number
9
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
1
Year of publication
2001
Pages
88 - 91
Database
ISI
SICI code
0163-3864(200101)64:1<88:CCGFTB>2.0.ZU;2-N
Abstract
Further phytochemical analysis of the bulbs of Ornithogalum saundersiae has yielded two new cytotoxic cholestane triglycosides (1 and 2). The structur es of these compounds were determined by spectroscopic analysis, including 2D NMR spectroscopic data, and the results of hydrolytic cleavage. Compound s 1 and 2 and several analogues were evaluated for their cytotoxicity again st HL-60 cells.