G. Di Bonaventura et al., Salmonella typhimurium-endocarditis secondary to an acquired environmentalinfection: A case report, MICROBIOLO, 24(1), 2001, pp. 85-89
A diabetic, cardiopathic and anemic 44-year-old farmer presented with a sev
en-day history of remittent fever with evening peaks. Two months before he
had undergone amputation of the V-finger of the left hand secondary to a ph
legmon caused by an agricultural injury. Prior to amputation, anaerobic cul
ture analysis of phlegmon-pus and selective procedures used to isolate Gram
-positive cocci and/or Pseudomonas spp. resulted negative. The diagnosis of
endocarditis was supported by isolation of S. typhimurium from blood and b
y echocardiography showing endocarditic lesions. The source of infection wa
s identified by PCR ribo-typing as the same Salmonella typhimurium strain t
hat was present, but not sought, both in the anatomic explanted tissues and
from blood samples of the patient. The infection was successfully treated
with a combination of gentamicin and ampicillin with consequent improvement
in the general clinical picture of the patient. We believe this is the fir
st reported case of S. typhimurium-endocarditis secondary to a phlegmon res
ulting from an environmental source of infection.