AN OBJECTIVE EVALUATION OF MUSCLE OXYGEN-CONTENT IN CLAUDICANTS RECEIVING DRUG-THERAPY

Authors
KOMIYAMA T SHIGEMATSU H YASUHARA H HOSOI Y MUTO T
Citation
T. Komiyama et al., AN OBJECTIVE EVALUATION OF MUSCLE OXYGEN-CONTENT IN CLAUDICANTS RECEIVING DRUG-THERAPY, International angiology, 15(3), 1996, pp. 215-218
Citations number
17
Categorie Soggetti
Cardiac & Cardiovascular System","Peripheal Vascular Diseas
Journal title
International angiology → ACNP
ISSN journal
03929590
Volume
15
Issue
3
Year of publication
1996
Pages
215 - 218
Database
ISI
SICI code
0392-9590(1996)15:3<215:AOEOMO>2.0.ZU;2-E
Abstract
The effects of medical treatment with a prostaglandin I-2 analog (bera prost sodium) were evaluated in 19 of 120 cases studied with near-infr ared spectroscopy (NIRS) from January 193 to September 1994. The relat ive changes in oxygenated (Oxy) and deoxygenated (Deo) hemoglobin (Hb) in the calf muscle were measured during a treadmill walking test and the subsequent recovery period. After medical treatment in these 19 ca ses, recovery time of OxyHb decreased in 10 cases, increased in 7 case s and remained unchanged in two cases. Pressure studies did not facili tate the assessment of changes in the severity of claudication. Our re sults demonstrate that NIPS can provide objective information regardin g the effects of medical therapy in claudicants.