Drastic photochemical stabilization of lomefloxacin through selective and efficient self-incorporation of its cationic form in anionic sodium dodecylsulfate (SDS) micelles

It is shown that a 30-fold photochemical stabilization of the highly photor eactive and photocarcinogenic fluoroquinolone lomefloxacin can be achieved through a selective and efficient sequestering of its cationic form by a su itable micellar system at neutral pH.