The purpose of the present study was to examine global meaning (i.e. the be
lief that life has purpose and coherence) and psychological adjustment in s
urvivors of bone marrow transplantation (BMT). Eighty-five survivors of BMT
participated in a telephone interview. Regression analyses demonstrated th
at after controlling for physical functioning, stressor severity, and gende
r, global meaning was inversely related to global psychological distress an
d BMT-related psychological distress (i.e. posttraumatic stress disorder-li
ke symptoms related to the cancer treatment). Global meaning was also posit
ively related to mental health aspects of quality of life (e.g. emotional f
unctioning and social functioning). These findings suggest that global mean
ing may be an important factor in the psychological adjustment of BMT survi
vors. Copyright (C) 2001 John Wiley & Sons, Ltd.