A young female patient with an androgen-secreting tumor: A rare malignant disease

Citation
A. Bozbora et al., A young female patient with an androgen-secreting tumor: A rare malignant disease, TUMORI, 86(6), 2000, pp. 487-488
Citations number
8
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
TUMORI
ISSN journal
03008916 → ACNP
Volume
86
Issue
6
Year of publication
2000
Pages
487 - 488
Database
ISI
SICI code
0300-8916(200011/12)86:6<487:AYFPWA>2.0.ZU;2-T
Abstract
A 23-year-old female patient presented with hirsutism and fatigue nine mont hs after delivery, Endocrine assessment showed high testesterone, DHEA-S an d androstenedione levels. Abdominal computed tomography and ultrasonography revealed the presence of a large tumor in the right renal region. Right ad renalectomy was performed resulting in a diagnosis of a functional adrenal tumor. Pathological examination showed a steroidogenically active tumor. Ad juvant chemotheraphy was administered postoperatively, At three months foll owing surgery all endocrinological tests normalized, but river metastases w ere detected by abdominal CT, Eight months after the operation the patient died of hepatic and renal failure, Androgen-secreting adrenal tumors are se en Very rarely yet the prognosis is poor due to their agressive nature.