H. Yamada et al., Medication management skill and regimen compliance are deteriorated in theelderly even without obvious dementia, YAKUGAKU ZA, 121(2), 2001, pp. 187-190
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
We investigated whether regimen comprehension deteriorated in the elderly p
atients who did not suffer from obvious dementia. Eligible patients were am
bulatory elderly patients who did not show any signs of dementia and could
visit our outpatient clinic by themselves. 138 patients (age: 43-89, 75 mal
es and 63 females, underlying diseases: hypertension, hyperlipidemia, arrhy
thmia etc.) were tested with a regimen comprehension scale (RCS: Jpn J Geri
at 1997; 34: 209-214). The differences in scores among individuals increase
d with age. Scores of 5 or less in the RCS were recorded in 10 out of 69 pa
tients aged 65 or more, but no such scores were recorded in younger patient
s (p<0.01). The 60 patients who scored less than full marks were classified
into two groups, the T-group (tutored by pharmacists), and a Non Tutored g
roup. RCS was tested again in both groups. Only in the T-group (n=28), did
the second scores increase significantly (from 7.2 +/- 0.9 to 8.6 +/- 2.0 (
mi +/- SD); p<0.01) after tutorial by pharmacists. Comparing the 7 patients
who obtained an RCS score of 5 or less and age- and gender-marched control
s who got full marks, there was no difference in the HDS-R test. These resu
lts suggest that even in elderly patients who did not show any signs of dem
entia, the regimen comprehension deteriorated with age, and tutorials in me
dication protocols were considered to be effective.