Background: Color blindness is a common hereditary X-linked disorder.
Objective: To investigate whether color blindness affects the ability to de
tect the presence of blood in body fluids.
Methods: Ten color-blind subjects and 20 sex- and age-matched control subje
cts were shown 94 photographs of stool, urine, or sputum. Frank blood was p
resent in 57 (61%) of the photographs. Surveys were done to determine if bo
ard-certified internists had ever considered whether color blindness would
affect detection of blood and whether an inquiry on color blindness was inc
luded in their standard medical interview.
Results: Color-blind subjects were significantly less able to identify corr
ectly whether pictures of body fluids showed blood compared with non-color-
blind controls (P = .001); the lowest rate of correct identifications occur
red with pictures of stool (median of 26 [70%] of 37 for color-blind subjec
ts vs 36.5 [99%] of 37 for controls; P<.001). The more severely color-blind
subjects were significantly less accurate than those with less severe colo
r deficiency (P = .009). Only 2 (10%) of the 21 physicians had ever conside
red the possibility that color blindness might affect the ability of patien
ts to detect blood, and none routinely asked their patients about color bli
ndness.
Conclusions: Color blindness impairs recognition of blood in body fluids. C
olor-blind individuals and their health care providers need to be made awar
e of this limitation.