RECURRENCE OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS IN THE POSTTRANSPLANT LUNGS OF A CYSTIC-FIBROSIS PATIENT

Cystic fibrosis (CF) is an autosomal recessive disease of exocrine ori gin. Allergic bronchopulmonary aspergillosis (ABPA) is an immunologic disorder caused by colonization of the airways with Aspergillus fumiga tus. A fumigatus has been cultured from posttransplant lungs in CF pat ients. Colonization of posttransplant lung with Aspergillus is a recog nized phenomenon. In this case report, however, we present a patient w ho developed ABPA both before and after lung transplant. This patient meets the criteria for ABPA based on serologic results. ABPA may be a complication in post-CF lung transplant patients and serologic analysi s should be considered when eosinophilia and pulmonary infiltrates or decline in lung function occurs.