A new Ti-15Zr-4Nb-4Ta alloy without V was implanted in rat tibiae for 6-48
weeks. The new bone formation surrounding the Ti implant in bone marrow, su
rface analysis of the Ti alloy after implantation. and metal concentrations
in dried bone tissue containing new bone were investigated. New bone was w
ell Formed around the Ti-15Zr-4Nb-4Ta alloy implanted in bone marrow. The m
ean thickness of the new bone increased up to 24 weeks after implantation,
and changes in the mean thickness thereafter, up to 48 weeks, were very sma
ll. The number of corrosion pits observed in the Ti-6Al-4V extra low inters
titial (ELI) alloy surface tended to be slightly more than that of the Ti-1
5Zr-4Nb-4Ta alloy implant. The concentrations of metal elements in the bone
tissue containing the new bone tended to increase slightly more than in be
nts without the implant. (C) 2001 Elsevier Science Ltd. All rights reserved
.