Translational regulation of the mRNA encoding the eukaryotic translation initiation factor 4E in Xenopus

Authors
Wakiyama, M Saigoh, M Ikeda, K Suzuki, A Miura, K
Citation
M. Wakiyama et al., Translational regulation of the mRNA encoding the eukaryotic translation initiation factor 4E in Xenopus, BIOS BIOT B, 65(1), 2001, pp. 229-231
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
65
Issue
1
Year of publication
2001
Pages
229 - 231
Database
ISI
SICI code
0916-8451(200101)65:1<229:TROTME>2.0.ZU;2-B
Abstract
We have cloned the cDNA for Xenopus eukaryotic translation initiation facto r 4E (eIF4E), Here we show that translation of a luciferase mRNA that conta ins the 5' untranslated region derived from Xenopus erF4E is active in fert ilized eggs, but is repressed in oocytes. The results suggest that the expr ession of Xenopus eIF4E is regulated at the translation level.