The ant colony algorithm, mimicking the cooperative search behavior of ants
in real life, has been employed for the dynamic optimization of fed-batch
bioreactors. To test the capability of this new heuristic algorithm, two we
ll-known and extensively studied systems have been chosen. The algorithm ra
pidly converges to optimal feed rate profiles, which maximize the overall p
roduction of the desired product and the profits in a computationally effic
ient and robust manner. The optimal profiles evolved are easy to implement
in plant operation. The algorithm compares favorably with the other known t
echniques.