Influence of highly active antiretroviral therapy on the outcome of subclinical visceral leishmaniasis in human immunodeficiency virus-infected patients

Authors
de la Rosa, R Pineda, JA Delgado, J Macias, J Morillas, F Martin-Sanchez, J Leal, M Sanchez-Quijano, A Lissen, E
Citation
R. De La Rosa et al., Influence of highly active antiretroviral therapy on the outcome of subclinical visceral leishmaniasis in human immunodeficiency virus-infected patients, CLIN INF D, 32(4), 2001, pp. 633-635
Citations number
15
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
32
Issue
4
Year of publication
2001
Pages
633 - 635
Database
ISI
SICI code
1058-4838(20010215)32:4<633:IOHAAT>2.0.ZU;2-0
Abstract
Seventeen human immunodeficiency virus-infected patients who were harboring untreated subclinical visceral leishmaniasis (VL) were prospectively follo wed up. None of the 11 patients who received highly active antiretroviral t herapy (HAART) presented with symptomatic VL during follow-up, whereas 2 ou t of 6 patients who received therapy other than HAART had an episode of ove rt kala-azar. These findings suggest that HAART does not induce the evoluti on of latent VL into symptomatic disease.