Wnt signaling: An embarrassment of receptors

Authors
Bejsovec, A
Citation
A. Bejsovec, Wnt signaling: An embarrassment of receptors, CURR BIOL, 10(24), 2000, pp. R919-R922
Citations number
18
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
10
Issue
24
Year of publication
2000
Pages
R919 - R922
Database
ISI
SICI code
0960-9822(200012)10:24<R919:WSAEOR>2.0.ZU;2-U
Abstract
Recent genetic studies in Drosophila and mouse have uncovered a new aspect of the Wnt signal transduction machinery. Mutations disrupting LDL-receptor related proteins produce loss-of-function Wnt phenotypes, suggesting that these cell surface molecules may represent essential co receptors for Wnt l igands.