Increasing evidence suggests that omega 3 fatty acids derived from fish and
fish oils may play a protective role in coronary heart disease and its man
y complications, through a variety of actions, including effects on lipids,
blood pressure. cardiac and vascular function, prostanoids, coagulation an
d immunological responses. Interesting differences between the effects of h
ighly purified eicosapentaenoic acid and docosahexaenoic acid are emerging,
which may be relevant in the choice of omega 3 fatty acid for incorporatio
n into food products. On the basis of our current knowledge, we believe it
is justified to recommend, particularly to high-risk populations, an increa
sed dietary intake of omega 3 fatty acids through the consumption of fish,
Curr Opin Lipidol 12:11-17. (C) 2001 Lippincott Williams & Wilkins.