Nanofabrication is playing an ever increasing role in science and technolog
y on the nanometer scale and will soon allow us to build systems of the sam
e complexity as found in nature. Conventional methods that emerged from mic
roelectronics are now used for the fabrication of structures for integrated
circuits, microelectro-mechanical-systems, microoptics and microanalytical
devices. Nonconventional or alternative approaches have changed the way we
pattern very fine structures and have brought about a new appreciation of
simple and low-cost techniques. We present an overview of some of these met
hods, paying particular attention to those which enable large-scale product
ion of lithographic patterns. We preface the review with a brief primer on
lithography and pattern transfer concepts. After reviewing the various patt
erning techniques, we discuss some recent application issues in the fields
of microelectronics, optoelectronics, magnetism as well as in biology and b
iochemistry.